CovidSeniorV1, Main, Exploration, bibRecord, 000989

A Severe COVID-19 Case Complicated by Right Atrium Thrombus.

Identifieur interne : 000989 ( Main/Exploration ); précédent : 000988; suivant : 000990

A Severe COVID-19 Case Complicated by Right Atrium Thrombus.

Auteurs : Anastasia Anthi [Grèce] ; Dimitrios Konstantonis [Grèce] ; Maria Theodorakopoulou [Grèce] ; Olympia Apostolopoulou [Grèce] ; Irene Karampela [Grèce] ; Georgia Konstantopoulou [Grèce] ; Stavroula Patsilinakou [Grèce] ; Apostolos Armaganidis [Grèce] ; George Dimopoulos [Grèce]

Source :

The American journal of case reports [ 1941-5923 ] ; 2020.

RBID : pubmed:32963216

Descripteurs français

KwdFr :
- Association thérapeutique (MeSH), Atrium du coeur (anatomopathologie), Atrium du coeur (imagerie diagnostique), Cardiopathies (imagerie diagnostique), Cardiopathies (thérapie), Cardiopathies (étiologie), Durée du séjour (MeSH), Fièvre (diagnostic), Fièvre (étiologie), Grèce (MeSH), Humains (MeSH), Indice de gravité de la maladie (MeSH), Infections à coronavirus (complications), Infections à coronavirus (diagnostic), Infections à coronavirus (thérapie), Mâle (MeSH), Pandémies (MeSH), Pneumopathie virale (complications), Pneumopathie virale (diagnostic), Pneumopathie virale (thérapie), Résultat thérapeutique (MeSH), Service hospitalier d'urgences (MeSH), Soins de réanimation (méthodes), Sujet âgé (MeSH), Syndrome respiratoire aigu sévère (complications), Syndrome respiratoire aigu sévère (diagnostic), Syndrome respiratoire aigu sévère (thérapie), Thrombose (imagerie diagnostique), Thrombose (thérapie), Thrombose (étiologie), Toux (diagnostic), Toux (étiologie), Unités de soins intensifs (MeSH), Échocardiographie transoesophagienne (méthodes), Études de suivi (MeSH), Évolution de la maladie (MeSH).
MESH :
- anatomopathologie : Atrium du coeur.
- diagnostic : Fièvre, Infections à coronavirus, Pneumopathie virale, Syndrome respiratoire aigu sévère, Toux.
- imagerie diagnostique : Atrium du coeur, Cardiopathies, Thrombose.
- méthodes : Soins de réanimation, Échocardiographie transoesophagienne.
- thérapie : Cardiopathies, Infections à coronavirus, Pneumopathie virale, Syndrome respiratoire aigu sévère, Thrombose.
- étiologie : Cardiopathies, Fièvre, Thrombose, Toux.
- Association thérapeutique, Durée du séjour, Grèce, Humains, Indice de gravité de la maladie, Infections à coronavirus, Mâle, Pandémies, Pneumopathie virale, Résultat thérapeutique, Service hospitalier d'urgences, Sujet âgé, Syndrome respiratoire aigu sévère, Unités de soins intensifs, Études de suivi, Évolution de la maladie.
Wicri :
- geographic : Grèce.

English descriptors

KwdEn :
- Aged (MeSH), Combined Modality Therapy (MeSH), Coronavirus Infections (complications), Coronavirus Infections (diagnosis), Coronavirus Infections (therapy), Cough (diagnosis), Cough (etiology), Critical Care (methods), Disease Progression (MeSH), Echocardiography, Transesophageal (methods), Emergency Service, Hospital (MeSH), Fever (diagnosis), Fever (etiology), Follow-Up Studies (MeSH), Greece (MeSH), Heart Atria (diagnostic imaging), Heart Atria (pathology), Heart Diseases (diagnostic imaging), Heart Diseases (etiology), Heart Diseases (therapy), Humans (MeSH), Intensive Care Units (MeSH), Length of Stay (MeSH), Male (MeSH), Pandemics (MeSH), Pneumonia, Viral (complications), Pneumonia, Viral (diagnosis), Pneumonia, Viral (therapy), Severe Acute Respiratory Syndrome (complications), Severe Acute Respiratory Syndrome (diagnosis), Severe Acute Respiratory Syndrome (therapy), Severity of Illness Index (MeSH), Thrombosis (diagnostic imaging), Thrombosis (etiology), Thrombosis (therapy), Treatment Outcome (MeSH).
MESH :
- geographic : Greece.
- complications : Coronavirus Infections, Pneumonia, Viral, Severe Acute Respiratory Syndrome.
- diagnosis : Coronavirus Infections, Cough, Fever, Pneumonia, Viral, Severe Acute Respiratory Syndrome.
- diagnostic imaging : Heart Atria, Heart Diseases, Thrombosis.
- etiology : Cough, Fever, Heart Diseases, Thrombosis.
- methods : Critical Care, Echocardiography, Transesophageal.
- pathology : Heart Atria.
- therapy : Coronavirus Infections, Heart Diseases, Pneumonia, Viral, Severe Acute Respiratory Syndrome, Thrombosis.
- Aged, Combined Modality Therapy, Disease Progression, Emergency Service, Hospital, Follow-Up Studies, Humans, Intensive Care Units, Length of Stay, Male, Pandemics, Severity of Illness Index, Treatment Outcome.

Abstract

BACKGROUND Recent studies demonstrated evidence of coagulation dysfunction in hospitalized patients with severe coronavirus disease 2019 (COVID-19) due to excessive inflammation, hypoxia, platelet activation, endothelial dysfunction, and stasis. Effective anticoagulation therapy may play a dominant role in the management of severe COVID-19 cases. CASE REPORT A 73-year-old man with a 6-day history of fever up to 38.5°C, dyspnea, cough, and fatigue was diagnosed with COVID-19. He had a past medical history significant for hypertension and coronary artery bypass grafting. Two days after hospital admission, the patient developed acute respiratory failure, requiring intubation, mechanical ventilation, and transfer to the intensive care unit (ICU). He received treatment including antibiotics, hydroxychloroquine, tocilizumab, vasopressors, prone positioning, and anticoagulation with enoxaparin at a prophylactic dose. After a 15-day ICU stay, the patient was hemodynamically stable but still hypoxemic; a transthoracic echocardiogram at that time, followed by a transesophageal echocardiogram for better evaluation, revealed the presence of a right atrium thrombus without signs of acute right ventricular dilatation and impaired systolic function. Since the patient was hemodynamically stable, we decided to treat him with conventional anticoagulation under close monitoring for signs of hemodynamic deterioration; thus, the prophylactic dose of enoxaparin was replaced by therapeutic dosing, which was a key component of the patient's successful outcome. Over the next few days he showed significant clinical improvement. The follow-up transesophageal echocardiogram 3 weeks after effective therapeutic anticoagulation revealed no signs of right heart thrombus. CONCLUSIONS The presented COVID-19 case, one of the first reported cases with evidence of right heart thrombus by transesophageal echocardiography, highlights the central role of diagnostic imaging strategies and the importance of adequate anticoagulation therapy in the management of severe COVID-19 cases in the ICU.

DOI: 10.12659/AJCR.926915
PubMed: 32963216
PubMed Central: PMC7520871

Affiliations:

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Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term>
<term>Combined Modality Therapy (MeSH)</term>
<term>Coronavirus Infections (complications)</term>
<term>Coronavirus Infections (diagnosis)</term>
<term>Coronavirus Infections (therapy)</term>
<term>Cough (diagnosis)</term>
<term>Cough (etiology)</term>
<term>Critical Care (methods)</term>
<term>Disease Progression (MeSH)</term>
<term>Echocardiography, Transesophageal (methods)</term>
<term>Emergency Service, Hospital (MeSH)</term>
<term>Fever (diagnosis)</term>
<term>Fever (etiology)</term>
<term>Follow-Up Studies (MeSH)</term>
<term>Greece (MeSH)</term>
<term>Heart Atria (diagnostic imaging)</term>
<term>Heart Atria (pathology)</term>
<term>Heart Diseases (diagnostic imaging)</term>
<term>Heart Diseases (etiology)</term>
<term>Heart Diseases (therapy)</term>
<term>Humans (MeSH)</term>
<term>Intensive Care Units (MeSH)</term>
<term>Length of Stay (MeSH)</term>
<term>Male (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Pneumonia, Viral (complications)</term>
<term>Pneumonia, Viral (diagnosis)</term>
<term>Pneumonia, Viral (therapy)</term>
<term>Severe Acute Respiratory Syndrome (complications)</term>
<term>Severe Acute Respiratory Syndrome (diagnosis)</term>
<term>Severe Acute Respiratory Syndrome (therapy)</term>
<term>Severity of Illness Index (MeSH)</term>
<term>Thrombosis (diagnostic imaging)</term>
<term>Thrombosis (etiology)</term>
<term>Thrombosis (therapy)</term>
<term>Treatment Outcome (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Association thérapeutique (MeSH)</term>
<term>Atrium du coeur (anatomopathologie)</term>
<term>Atrium du coeur (imagerie diagnostique)</term>
<term>Cardiopathies (imagerie diagnostique)</term>
<term>Cardiopathies (thérapie)</term>
<term>Cardiopathies (étiologie)</term>
<term>Durée du séjour (MeSH)</term>
<term>Fièvre (diagnostic)</term>
<term>Fièvre (étiologie)</term>
<term>Grèce (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Indice de gravité de la maladie (MeSH)</term>
<term>Infections à coronavirus (complications)</term>
<term>Infections à coronavirus (diagnostic)</term>
<term>Infections à coronavirus (thérapie)</term>
<term>Mâle (MeSH)</term>
<term>Pandémies (MeSH)</term>
<term>Pneumopathie virale (complications)</term>
<term>Pneumopathie virale (diagnostic)</term>
<term>Pneumopathie virale (thérapie)</term>
<term>Résultat thérapeutique (MeSH)</term>
<term>Service hospitalier d'urgences (MeSH)</term>
<term>Soins de réanimation (méthodes)</term>
<term>Sujet âgé (MeSH)</term>
<term>Syndrome respiratoire aigu sévère (complications)</term>
<term>Syndrome respiratoire aigu sévère (diagnostic)</term>
<term>Syndrome respiratoire aigu sévère (thérapie)</term>
<term>Thrombose (imagerie diagnostique)</term>
<term>Thrombose (thérapie)</term>
<term>Thrombose (étiologie)</term>
<term>Toux (diagnostic)</term>
<term>Toux (étiologie)</term>
<term>Unités de soins intensifs (MeSH)</term>
<term>Échocardiographie transoesophagienne (méthodes)</term>
<term>Études de suivi (MeSH)</term>
<term>Évolution de la maladie (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Greece</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Atrium du coeur</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term>
<term>Cough</term>
<term>Fever</term>
<term>Pneumonia, Viral</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Fièvre</term>
<term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
<term>Syndrome respiratoire aigu sévère</term>
<term>Toux</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Heart Atria</term>
<term>Heart Diseases</term>
<term>Thrombosis</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cough</term>
<term>Fever</term>
<term>Heart Diseases</term>
<term>Thrombosis</term>
</keywords>
<keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Atrium du coeur</term>
<term>Cardiopathies</term>
<term>Thrombose</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Critical Care</term>
<term>Echocardiography, Transesophageal</term>
</keywords>
<keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Soins de réanimation</term>
<term>Échocardiographie transoesophagienne</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Heart Atria</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Coronavirus Infections</term>
<term>Heart Diseases</term>
<term>Pneumonia, Viral</term>
<term>Severe Acute Respiratory Syndrome</term>
<term>Thrombosis</term>
</keywords>
<keywords scheme="MESH" qualifier="thérapie" xml:lang="fr"><term>Cardiopathies</term>
<term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
<term>Syndrome respiratoire aigu sévère</term>
<term>Thrombose</term>
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<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Cardiopathies</term>
<term>Fièvre</term>
<term>Thrombose</term>
<term>Toux</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Combined Modality Therapy</term>
<term>Disease Progression</term>
<term>Emergency Service, Hospital</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Intensive Care Units</term>
<term>Length of Stay</term>
<term>Male</term>
<term>Pandemics</term>
<term>Severity of Illness Index</term>
<term>Treatment Outcome</term>
</keywords>
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<term>Durée du séjour</term>
<term>Grèce</term>
<term>Humains</term>
<term>Indice de gravité de la maladie</term>
<term>Infections à coronavirus</term>
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<term>Pandémies</term>
<term>Pneumopathie virale</term>
<term>Résultat thérapeutique</term>
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<term>Sujet âgé</term>
<term>Syndrome respiratoire aigu sévère</term>
<term>Unités de soins intensifs</term>
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<front><div type="abstract" xml:lang="en">BACKGROUND Recent studies demonstrated evidence of coagulation dysfunction in hospitalized patients with severe coronavirus disease 2019 (COVID-19) due to excessive inflammation, hypoxia, platelet activation, endothelial dysfunction, and stasis. Effective anticoagulation therapy may play a dominant role in the management of severe COVID-19 cases. CASE REPORT A 73-year-old man with a 6-day history of fever up to 38.5°C, dyspnea, cough, and fatigue was diagnosed with COVID-19. He had a past medical history significant for hypertension and coronary artery bypass grafting. Two days after hospital admission, the patient developed acute respiratory failure, requiring intubation, mechanical ventilation, and transfer to the intensive care unit (ICU). He received treatment including antibiotics, hydroxychloroquine, tocilizumab, vasopressors, prone positioning, and anticoagulation with enoxaparin at a prophylactic dose. After a 15-day ICU stay, the patient was hemodynamically stable but still hypoxemic; a transthoracic echocardiogram at that time, followed by a transesophageal echocardiogram for better evaluation, revealed the presence of a right atrium thrombus without signs of acute right ventricular dilatation and impaired systolic function. Since the patient was hemodynamically stable, we decided to treat him with conventional anticoagulation under close monitoring for signs of hemodynamic deterioration; thus, the prophylactic dose of enoxaparin was replaced by therapeutic dosing, which was a key component of the patient's successful outcome. Over the next few days he showed significant clinical improvement. The follow-up transesophageal echocardiogram 3 weeks after effective therapeutic anticoagulation revealed no signs of right heart thrombus. CONCLUSIONS The presented COVID-19 case, one of the first reported cases with evidence of right heart thrombus by transesophageal echocardiography, highlights the central role of diagnostic imaging strategies and the importance of adequate anticoagulation therapy in the management of severe COVID-19 cases in the ICU.</div>
</front>
</TEI>
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<DateCompleted><Year>2020</Year>
<Month>10</Month>
<Day>13</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>10</Month>
<Day>13</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1941-5923</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>21</Volume>
<PubDate><Year>2020</Year>
<Month>Sep</Month>
<Day>23</Day>
</PubDate>
</JournalIssue>
<Title>The American journal of case reports</Title>
<ISOAbbreviation>Am J Case Rep</ISOAbbreviation>
</Journal>
<ArticleTitle>A Severe COVID-19 Case Complicated by Right Atrium Thrombus.</ArticleTitle>
<Pagination><MedlinePgn>e926915</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.12659/AJCR.926915</ELocationID>
<Abstract><AbstractText>BACKGROUND Recent studies demonstrated evidence of coagulation dysfunction in hospitalized patients with severe coronavirus disease 2019 (COVID-19) due to excessive inflammation, hypoxia, platelet activation, endothelial dysfunction, and stasis. Effective anticoagulation therapy may play a dominant role in the management of severe COVID-19 cases. CASE REPORT A 73-year-old man with a 6-day history of fever up to 38.5°C, dyspnea, cough, and fatigue was diagnosed with COVID-19. He had a past medical history significant for hypertension and coronary artery bypass grafting. Two days after hospital admission, the patient developed acute respiratory failure, requiring intubation, mechanical ventilation, and transfer to the intensive care unit (ICU). He received treatment including antibiotics, hydroxychloroquine, tocilizumab, vasopressors, prone positioning, and anticoagulation with enoxaparin at a prophylactic dose. After a 15-day ICU stay, the patient was hemodynamically stable but still hypoxemic; a transthoracic echocardiogram at that time, followed by a transesophageal echocardiogram for better evaluation, revealed the presence of a right atrium thrombus without signs of acute right ventricular dilatation and impaired systolic function. Since the patient was hemodynamically stable, we decided to treat him with conventional anticoagulation under close monitoring for signs of hemodynamic deterioration; thus, the prophylactic dose of enoxaparin was replaced by therapeutic dosing, which was a key component of the patient's successful outcome. Over the next few days he showed significant clinical improvement. The follow-up transesophageal echocardiogram 3 weeks after effective therapeutic anticoagulation revealed no signs of right heart thrombus. CONCLUSIONS The presented COVID-19 case, one of the first reported cases with evidence of right heart thrombus by transesophageal echocardiography, highlights the central role of diagnostic imaging strategies and the importance of adequate anticoagulation therapy in the management of severe COVID-19 cases in the ICU.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Anthi</LastName>
<ForeName>Anastasia</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>2nd Department of Critical Care, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Konstantonis</LastName>
<ForeName>Dimitrios</ForeName>
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<AffiliationInfo><Affiliation>2nd Department of Critical Care, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.</Affiliation>
</AffiliationInfo>
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<AffiliationInfo><Affiliation>2nd Department of Critical Care, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.</Affiliation>
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<AffiliationInfo><Affiliation>2nd Department of Critical Care, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.</Affiliation>
</AffiliationInfo>
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<Initials>I</Initials>
<AffiliationInfo><Affiliation>2nd Department of Critical Care, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.</Affiliation>
</AffiliationInfo>
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<Initials>G</Initials>
<AffiliationInfo><Affiliation>2nd Department of Critical Care, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.</Affiliation>
</AffiliationInfo>
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<ForeName>Stavroula</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>2nd Department of Critical Care, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Armaganidis</LastName>
<ForeName>Apostolos</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>2nd Department of Critical Care, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Dimopoulos</LastName>
<ForeName>George</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>2nd Department of Critical Care, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.</Affiliation>
</AffiliationInfo>
</Author>
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<Language>eng</Language>
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<Month>09</Month>
<Day>23</Day>
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<CitationSubset>IM</CitationSubset>
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<ReferenceList><Reference><Citation>Am J Med Case Rep. 2020;8(8):225-228</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32542188</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Thromb Res. 2020 Sep;193:98</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32534328</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Eur Heart J Cardiovasc Imaging. 2020 Sep 1;21(9):1054</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32338707</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Thromb Res. 2020 Jul;191:9-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32353746</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2020 May 21;382(21):e70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32374956</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Am Coll Cardiol. 2020 Jun 16;75(23):2950-2973</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32311448</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Circulation. 2020 Jul 14;142(2):184-186</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32330083</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2020 Apr 30;382(18):1708-1720</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32109013</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Respir Med Res. 2020 Nov;78:100759</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32474397</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2020 Mar 28;395(10229):1054-1062</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32171076</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Thromb Haemost. 2020 Jun;18(6):1421-1424</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32271988</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>JACC Case Rep. 2020 Jul 15;2(9):1391-1396</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32835284</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Am Soc Echocardiogr. 2020 Aug;33(8):1040-1047</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32600742</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>CASE (Phila). 2020 Aug;4(4):200-203</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32426575</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Eur Respir J. 2020 Jul 30;56(1):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32554532</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Thromb Res. 2020 Jul;191:145-147</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32291094</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Crit Care Med. 2020 Sep;48(9):e783-e790</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32459672</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Circulation. 2020 Jun 2;141(22):1739-1741</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32271624</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
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A Severe COVID-19 Case Complicated by Right Atrium Thrombus.

A Severe COVID-19 Case Complicated by Right Atrium Thrombus.

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